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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-143
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79
Methods transfection, luciferase reporter assay, viability assay, apoptosis assay, transwell assay, qRT-PCR, Western blot
Expression pattern down-regulated
Functional description miR-143 exerted tumor suppressive effects on Y79 cells by targeting RUNX2, along with inhibition of the PI3K/AKT/mTOR pathways.
PubMed ID 30551533
Year 2019
Title Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma.
Drug-related ncRNA NO

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