ncRNA name | hsa-miR-143 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell line Y79 |
Methods | transfection, luciferase reporter assay, viability assay, apoptosis assay, transwell assay, qRT-PCR, Western blot |
Expression pattern | down-regulated |
Functional description | miR-143 exerted tumor suppressive effects on Y79 cells by targeting RUNX2, along with inhibition of the PI3K/AKT/mTOR pathways. |
PubMed ID | 30551533 |
Year | 2019 |
Title | Knockdown of lncRNA-H19 inhibits cell viability, migration and invasion while promotes apoptosis via microRNA-143/RUNX2 axis in retinoblastoma. |
Drug-related ncRNA | NO |
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